ShareLocalization of freezing injury in articular cartilage.
Author(s) : MULDREW K., HURTIG M., NOVAK K., SCHACHAR N., MCGANN L. E.
Type of article: Article
Summary
Osteochondral dowels taken from the femoral condyles of sheep were subjected to graded freezing in the presence and absence of a cryoprotectant (10% DMSO). In general, tissue response was similar to that of cell suspensions, showing at least two mechanisms of injury acting on the cells: one at slow cooling rates and another at rapid cooling rates. The primary effect of DMSO was to reduce injury due to slow cooling. When the location of injury within the tissue was examined, it was found that chondrocytes of the intermediate layer were injured more extensively than those of either the deep or superficial layers.
Details
- Original title: Localization of freezing injury in articular cartilage.
- Record ID : 1995-1214
- Languages: English
- Source: Cryobiology - vol. 31 - n. 1
- Publication date: 1994/02
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