PLATELET CRYOPRESERVATION.

Author(s) : SHEPHERD K. M.

Type of article: Article

Summary

PLATELETS WERE CRYOPRESERVED IN THE PRESENCE OF 5% DMSO AT A CONTROLLED RATE OF FREEZING OF 1 K/MIN AND STORED IN LIQUID NITROGEN FOR UP TO 3 MONTHS. A SIGNIFICANT LOSS OF PLATELETS OCCURRED AT THE PLATELET CONCENTRATION STEP THROUGH ADHESION OF PLATELETS TO THE BAG WALLS. A SMALL LOSS OF PLATELET AGGREGATION WAS SEEN WITH ALL AGENTS FOLLOWING CRYOPRESERVATION. NO SIGNIFICANT CHANGES IN AGGREGATION OR RECOVERY WERE SEEN OVER THE 3 MONTHS' STORAGE PERIOD. DMSO WAS SHOWN TO HAVE NO DELETERIOUS EFFECT ON PLATELET FUNCTION IN VITRO.

Details

  • Original title: PLATELET CRYOPRESERVATION.
  • Record ID : 1985-0343
  • Languages: English
  • Source: Cryobiology - vol. 21 - n. 1
  • Publication date: 1984

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