Share

IIR document

Regional flow motion and heat energy balance analysis of a 10,000 class pharmaceutical cleanroom with secondary return air conditioning system.

Author(s) : ZHAO F. Y., CHENG J., LIU B., HUANG Z. R., ZHANG Y. J., LI X.

Type of article: IJR article

Summary

Improving air quality in occupied area has always been the core focus of ventilation design in cleanrooms. A 10,000 class pharmaceutical cleanroom, with secondary return system, was firstly introduced. Full computational fluid dynamics procedure validated by on-site measurements was then applied to model such cleanroom airflow and particle transport. Energy balance of this ventilation system was also analyzed. Details of room airflow and contaminant fields for the specific zone (above the device and around the human body) were subsequently analyzed concerning the effect of delivering ventilation flow rate and return air volume. Representative parameters, mean age of air, contaminant removal effectiveness, and air change efficiency at the occupied zone and the whole space were evaluated. Results demonstrate that promotion of the return air volume in the occupied area could appropriately reduce pollutant concentration level. Moreover, an increase in ACH (air change rate per hour) did not always shorten the local age of air near the equipment. For a large ACH, it not only will raise the dust around the machine again, it will also cause uncomfortable flow draft. Additionally, when ACH = 20 h−1 and 25 h−1 were achieved respectively, the age of air was reduced by 32% and 21.4% in the whole room and further done by 31.1% and 23.5% in the occupied zone; with identical changes, room air change efficiency (RACE) was achieved at 49.3 % and 50.4 %, respectively. It shows that the increase of ACH seems to have little effect on the air change efficiency. When ACH increases from 15 h−1 to 20 h−1, the efficiency of pollutant removal at the occupied zone will not be significantly improved ( 1.78).

Available documents

Format PDF

Pages: 237-249

Available

  • Public price

    20 €

  • Member price*

    Free

* Best rate depending on membership category (see the detailed benefits of individual and corporate memberships).

Details

  • Original title: Regional flow motion and heat energy balance analysis of a 10,000 class pharmaceutical cleanroom with secondary return air conditioning system.
  • Record ID : 30028714
  • Languages: English
  • Subject: Technology
  • Source: International Journal of Refrigeration - Revue Internationale du Froid - vol. 129
  • Publication date: 2021/09
  • DOI: http://dx.doi.org/10.1016/j.ijrefrig.2021.03.021
  • Document available for consultation in the library of the IIR headquarters only.

Links


See other articles in this issue (32)
See the source

Indexing