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Room temperature vulcanizing silicone elastomers as model material for studying organ cryopreservation.

Author(s) : BAUDOT A., HUDELOT J. P., PEYRIDIEU J. F., MAZUER J., ODIN J.

Summary

Long-term preservation of organs at cryo-temperatures is one of the main parameters which determine the later development of homografts. The only way to cryopreserve whole organs is to vitrify them. Heat transfer during cooling and warming can be studied on model organs. Room temperature vulcanized silicons (from Rhône-Poulenc, France), which are cast in the form of cylinders and hollow spheres are used to model the human kidney and heart. The value of this material is in its capacity of exhibiting either a crystalline or amorphous state, depending of the cooling rate, as is observed for the organs when they are impregnated by a cryoprotectant. Results are given on the cooling rates inside the model organs and compared with a numerical simulation.

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Pages: 52-59

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Details

  • Original title: Room temperature vulcanizing silicone elastomers as model material for studying organ cryopreservation.
  • Record ID : 1996-1215
  • Languages: English
  • Source: For a Better Quality of Life. 19th International Congress of Refrigeration.
  • Publication date: 1995/08/20
  • Document available for consultation in the library of the IIR headquarters only.

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