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The influence of cryopreservation on cytokine production by human T lymphocytes.

Author(s) : WANG S. Y., HSU M. L., TZENG C. H., HSU H. C., HO C. K.

Type of article: Article

Summary

Cryopreservation of human lymphocytes is of clinical importance for some immunotherapeutic regimens and diagnostic investigations. Compared with PHA-activated fresh T cells, all the considered cytokines did not diminish in their levels in conditioned medium from PHA-treated frozen T cells thawed at each storage period, suggesting that cryopreservation could well retain the cytokine-producing activity of human T lymphocytes. In addition, results also revealed that cryopreservation rendered T lymphocytes more responsive to PHA in IL-2 production than fresh T cells.

Details

  • Original title: The influence of cryopreservation on cytokine production by human T lymphocytes.
  • Record ID : 1999-3896
  • Languages: English
  • Source: Cryobiology - vol. 37 - n. 1
  • Publication date: 1998/08

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