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TISSUE BANKING: PRESENT STATUS AND FUTURE PROMISE.

Author(s) : MERYMAN H. T.

Summary

CENTRAL TO A TRUE TISSUE BANKING SYSTEMIS THE NECESSITY FOR LONG-TERM STORAGE. ALTHOUGH SOME TISSUES CAN BE STORED FOR MANY HOURS OR EVEN DAYS AT REFRIGERATOR TEMPERATURE, MORE COMPLEX TISSUES AND ORGANS ARE SEVERELY LIMITED IN THE EXTENT TO WHICH THEY WILL TOLERATE STORAGE. THE ONLY TECHNIQUE SO FAR REPORTED THAT PROMISES TO PREVENT THE FORMATION OF ICE ALTOGETHER INVOLVES THE USE OF CRYOPROTECTIVE SOLUTES AT HIGH CONCENTRATION PLUS THE IMPOSITION OF HYDROSTATIC PRESSURE WHICH, LIKE CRYOPROTECTIVE SOLUTES, ALSO LOWERS THE MELTING POINT AND REDUCES THE AMOUNT OF ICE FORMED. SINCE ICE CAN ALSO FORM DURING REWARMING, REWARMING MUST BE VERY RAPID. C. B.

Details

  • Original title: TISSUE BANKING: PRESENT STATUS AND FUTURE PROMISE.
  • Record ID : 1989-0351
  • Languages: English
  • Publication date: 1987/08/02
  • Source: Source: Proc. 3rd natl. Sch. Cryobiol. Freeze-drying, Sofia
    43-53; 50 ref.
  • Document available for consultation in the library of the IIR headquarters only.

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