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A NEWLY DEVELOPED SYSTEM FOR COOLING AND PRESERVING ISOLATED LIVER AT SUBZERO TEMPERATURES.

[In Japanese. / En japonais.]

Author(s) : KUSUMOTO K.

Type of article: Article

Summary

WISTAR RAT LIVERS WERE COOLED TO 269 K (-4 DEG C) AND REWARMED TO 277 K (4 DEG C) BY THIS SYSTEM USING A 10% DMSO SOLUTION. LIGHT MICROSCOPIC FINDINGS OF LIVER PRESERVED AT 269 K FOR 24 HOURS SHOWED SLIGHT CELLULAR ATROPHY AND SINUSOIDAL DILATATION. LIVER PRESERVED AT 277 K FOR 24 HOURS SHOWED DIFFUSED NECROSIS OF THE CELLS AND ARCHITECTURAL DESTRUCTION OF LOBULES. THE SYSTEM IS USEFUL FOR CONTROLLING LIVER TEMPERATURE IN COOLING AND REWARMING AND VIABILITY AT SUBZERO TEMPERATURES CONTROLLED BYTHIS SYSTEM IS BETTER THAN THAT OF LIVERS PRESERVED ABOVE 273 K (0 DEG C).

Details

  • Original title: [In Japanese. / En japonais.]
  • Record ID : 1988-2532
  • Languages: Japanese
  • Source: Low Temperature Medicine - vol. 13 - n. 2
  • Publication date: 1987
  • Document available for consultation in the library of the IIR headquarters only.

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