ShareVARIATION OF COOLING RATE AND CONCENTRATION OF DMSO ON RABBIT KIDNEY FUNCTION.
Author(s) : GUTTMAN F. M.
Type of article: Article
Summary
RABBIT KIDNEY FUNCTION WAS ASSESSED IN VITRO AFTER CRYOPROTECTION WITH EITHER 3 OR 4 M DMSO. THIS MODEL CAN BE SHOWN TO RESPOND TO VARIOUS ISCHEMIC-LIKE STATES RESULTING IN POOR OR ABSENTFUNCTION. VARIATIONS IN THE RATE OF COOLING WERE CARRIED OUT. IN GENERAL, CREATININE CLEARANCE, SODIUM AND GLUCOSE REABSORPTION ARE PRESERVED WITH A FAIR DEGREE OF SUCCESS AFTER COOLING TO 263, 258 AND 253 K (-10, -15 AND -20 DEG C), WHEN THE RATE OF COOLING IS 0.0166 K/SEC. WHEN A COOLING RATE OF 0.008 K/SEC IS USED, RENAL FUNCTION IS SIGNIFICANTLY REDUCED.
Details
- Original title: VARIATION OF COOLING RATE AND CONCENTRATION OF DMSO ON RABBIT KIDNEY FUNCTION.
- Record ID : 1987-2025
- Languages: English
- Source: Cryobiology - vol. 23 - n. 6
- Publication date: 1986
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