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Devitrification in butane-2,3-diol solutions containing anti-freeze peptid.

Author(s) : SUTTON R. L., PEGG D. E.

Type of article: Article

Summary

Cryopreservation of viable tissues and organs by vitrification requires that devitrification (freezing) be presented during warming. The authors report that a synthetic antifreeze, modelled on the natural peptid found in the Winter Flounder Pseudopleuronectes americanus, substantially raises the devitrification temperature of solutions of the cryoprotectant butane-2,3-diol. The addition of 1% w/w peptid reduces the minimum warming rate to avoid devitrification of a 30% solution by a factor of 7000.

Details

  • Original title: Devitrification in butane-2,3-diol solutions containing anti-freeze peptid.
  • Record ID : 1994-1252
  • Languages: English
  • Source: Cryo-Letters - vol. 14 - n. 1
  • Publication date: 1993/01
  • Document available for consultation in the library of the IIR headquarters only.

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