Ethylene glycol permeation and toxicity in the rabbit common carotid artery.
Author(s) : WUSTEMAN M., BUSZA A., BOYLAN S., HAYES A., PEGG D.
Type of article: Article
Summary
Ethylene glycol is shown to be a cryoprotectant that permeates sufficiently rapidly into small elastic arteries to achieve cryoprotective tissue concentrations after relatively short periods of exposure. It is nontoxic at temperatures close to 0 deg C, both for the smooth muscle and the vascular endothelium, even at concentrations approaching those capable of causing vitrification. Therefore, ethylene glycol warrants further investigation as a possible cryoprotectant for the preservation of arteries for clinical use.
Details
- Original title: Ethylene glycol permeation and toxicity in the rabbit common carotid artery.
- Record ID : 1996-1892
- Languages: English
- Source: Cryobiology - vol. 32 - n. 5
- Publication date: 1995/10
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The effect of cooling rate and temperature on t...
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- Date : 1996/08
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- Date : 1995/10
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- Author(s) : SONG Y. C., HUNT C. J., PEGG D. E.
- Date : 1994/08
- Languages : English
- Source: Cryobiology - vol. 31 - n. 4
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- Author(s) : SOMMERFELD V., NIEMANN H.
- Date : 1999/03
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- Source: Cryobiology - vol. 38 - n. 2
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