Evidence for two modes of hypothermia damage in five cell lines.

Author(s) : KRUUV J., GLOFCHESKI D. J., LEPOCK J. R.

Type of article: Article

Summary

The Arrhenius plots of inactivation (killing) rates of five mammalian cell lines, V-79 Chinese hamster lung, mouse L-929, mouse neuroblastoma, human 18LU, and human erythrocytes, exposed to hypothermia contain a break somewhere between 5 and 10 deg C which corresponds to the minimum inactivation rate. It is suggested that the optimum aerobic hypothermic storage temperature for human cells and tissues is not 0 deg C, but somewhere in the range of 5 to 10 deg C.

Details

  • Original title: Evidence for two modes of hypothermia damage in five cell lines.
  • Record ID : 1996-0526
  • Languages: English
  • Source: Cryobiology - vol. 32 - n. 2
  • Publication date: 1995/04

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