ShareFactors influencing survival of mammalian cells exposed to hypothermia.
Author(s) : KRUUV J., LEPOCK J. R.
Type of article: Article
Summary
The Arrhenius plot of inactivation (killing) rates of V-79 Chinese hamster cells exposed to hypothermia in air-equilibrated (aerobic) medium contains a break at about 8 deg C, which corresponds to the minimum inactivation rate. With or without severe hypoxia, 10 deg C storage is preferable to 5 deg C storage in the cell line. Extrapolated to organ storage, the results may imply that if warm ischemia (prehypothermic hypoxia) has occurred, subsequent hypoxic hypothermic perfusion storage may be preferable to aerobic hypothermic perfusion storage.
Details
- Original title: Factors influencing survival of mammalian cells exposed to hypothermia.
- Record ID : 1996-0527
- Languages: English
- Source: Cryobiology - vol. 32 - n. 2
- Publication date: 1995/04
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Indexing
- Themes: Cryobiology, cryomedicine: general information
- Keywords: Cryobiology; Cell; Survival; Mammal; Hypothermia
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Evidence for two modes of hypothermia damage in...
- Author(s) : KRUUV J., GLOFCHESKI D. J., LEPOCK J. R.
- Date : 1995/04
- Languages : English
- Source: Cryobiology - vol. 32 - n. 2
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A two-step reversible-irreversible model can ac...
- Author(s) : MUENCH J. L., KRUUV J., LEPOCK J. R.
- Date : 1996/04
- Languages : English
- Source: Cryobiology - vol. 33 - n. 2
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Phospholipid peroxidation in isolated perfused ...
- Author(s) : YTREHUS K., ASPANG E. M.
- Date : 1994/06
- Languages : English
- Source: Cryobiology - vol. 31 - n. 3
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Improved rat heart function after low calcium i...
- Author(s) : LIU B., LOPASCHUK G. D., WANG L. C. H.
- Date : 1994/06
- Languages : English
- Source: Cryobiology - vol. 31 - n. 3
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Dream of preservation for active life.
- Author(s) : TAKANO M.
- Date : 1994
- Languages : Japanese
- Source: Refrigeration - vol. 69 - n. 795
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