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Low-temperature freeze-drying of red blood cells: influence of the shelf temperature.

Tieftemperature-Gefriertrocknung von Erythrozyten: Der Einfluss der Stellflächentemperatur.

Author(s) : RINDLER V., HESCHEL I., SCHWINDKE P., et al.

Type of article: Article

Summary

Using a self-designed low-temperature freeze-drying device, human red blood cells were freeze-dried at selected shelf temperatures between -5 and -65 deg C. After rehydration of the samples, the highest recovery rate (higher than 15%) was measured at a shelf temperature of -35%. Both increased and decreased shelf temperatures led to a significant reduction in recovery. To interpret this effect, a model based on the superposition of two contrary damaging mechanisms is suggested.

Details

  • Original title: Tieftemperature-Gefriertrocknung von Erythrozyten: Der Einfluss der Stellflächentemperatur.
  • Record ID : 2000-2246
  • Languages: German
  • Source: KI Luft Kältetech. - n. 6
  • Publication date: 1999/06
  • Document available for consultation in the library of the IIR headquarters only.

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