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Morphological and functional alterations in endothelium, smooth muscle, and nerve fibers in rabbit aorta after storage at 4 deg C.

Author(s) : KRISTEK F., TOROK J., SIKULOVA J.

Type of article: Article

Summary

Structural and implied functional changes in endothelial cells, smooth muscle cells, and nerve fibers in rabbit aorta were studied after storage in cold Krebs solution. Rings from the thoracic aorta were stored for 2, 4, 6, and 8 days in a refrigerator at 4 deg C. Subsequently they were examined after 6 hours in an organ bath at 37 deg C and processed for transmission electron microscopy. The earliest and most prominent structural changes were observed in nerve fibers and varicosities. The most resistant cells were smooth muscle cells, showing only slight alterations during the whole period. Contraction of aortic rings in response to transmural nerve stimulation (8 hertz) gradually decreased with the length of cold storage.

Details

  • Original title: Morphological and functional alterations in endothelium, smooth muscle, and nerve fibers in rabbit aorta after storage at 4 deg C.
  • Record ID : 1994-1864
  • Languages: English
  • Source: Cryobiology - vol. 30 - n. 4
  • Publication date: 1993/08

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