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ON THE DEFINITION OF AN AVERAGE COOLING RATE DURING CELL FREEZING.

Author(s) : HAYES L. J.

Type of article: Article

Summary

THE FIRST TECHNIQUE AVERAGES THE TRANSIENT COOLING RATE AS A FUNCTION OF TIME, AND THE SECOND AS A FUNCTION OF TEMPERATURE. THE APPLICATION WHICH MOTIVATES THIS WORK IS THE INTERPRETATION OF CELL SURVIVAL SIGNATURES DURING CRYOPRESERVATION. VALUES OF THE AVERAGE COOLING RATE ARE CALCULATED WITH BOTH TECHNIQUES FOR A NUMBER OF HYPOTHETICAL AND ACTUAL COOLING PATTERNS. THE RESULTS CLEARLY INDICATE THAT DIFFERENT AVERAGING TECHNIQUES YIELD DIFFERENT VALUES OF COOLING RATE AND THAT THERE IS A NEED TO OBTAIN ACCURATE RATE INFORMATION RELATED TO CELL INJURY.

Details

  • Original title: ON THE DEFINITION OF AN AVERAGE COOLING RATE DURING CELL FREEZING.
  • Record ID : 1984-2469
  • Languages: English
  • Source: Cryo-Letters - vol. 5 - n. 2
  • Publication date: 1984
  • Document available for consultation in the library of the IIR headquarters only.

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