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Experimental studies on cryopreservation of pancreatic islet.

[In Japanese. / En japonais.]

Author(s) : NAKAGAWARA G., KIMURA T., HIRAIZUMI Y., FUJISAWA K., NOTE M.

Type of article: Article

Summary

Cryopreservation using a rapid cooling rate of 25 K/min was found to be as effective as a slow cooling rate of 1 K/min for hamster islet, but it did not appear that this treatment reduced islet vulnerability to xenogenic graft rejection. Islet cells dissociated from rat islets could be cryopreserved by using a cooling rate of 1 K/min, and were aggregated into pseudoislets in an in-vitro culture. Using this treatment, there was a significant prolongation of survival time in allogenic transplantation.

Details

  • Original title: [In Japanese. / En japonais.]
  • Record ID : 1994-2557
  • Languages: Japanese
  • Source: Cryomedicine - vol. 19 - n. 1
  • Publication date: 1993/03
  • Document available for consultation in the library of the IIR headquarters only.

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