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PROPANE-1,2-DIOL AS A POTENTIAL COMPONENT OF A VITRIFICATION SOLUTION FOR CORNEAS.

Author(s) : RICH S. J., ARMITAGE W. J.

Type of article: Article

Summary

ANY METHOD OF CRYOPRESERVATION OF THE CORNEA MUST MAINTAIN INTEGRITY OF THE CORNEAL ENDOTHELIUM. DURING FREEZING, THE FORMATION OF ICE DAMAGES THE ENDOTHELIUM, AND VITRIFICATION HAS BEEN SUGGESTED AS A MEANS OF ACHIEVING ICE-FREE CRYOPRESERVATION. TO ACHIEVE VITRIFICATION AT PRACTICABLE COOLING RATES, TISSUES MUST BE EQUILIBRATED WITH HIGH CONCENTRATIONS OF CRYOPROTECTANTS. IN THE STUDY, THE EFFECTS OF PROPANE-1,2-DIOL ON THE STRUCTURE AND FUNCTION OF RABBIT CORNEAL ENDOTHELIUM WERE STUDIED.

Details

  • Original title: PROPANE-1,2-DIOL AS A POTENTIAL COMPONENT OF A VITRIFICATION SOLUTION FOR CORNEAS.
  • Record ID : 1991-0887
  • Languages: English
  • Source: Cryobiology - vol. 27 - n. 1
  • Publication date: 1990

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