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STABILITY OF THE AMORPHOUS STATE IN THE SYSTEM WATER-1.2-PROPANEDIOL-METHANOL.

Author(s) : MEHL P., BOUTRON P.

Type of article: Article

Summary

AS 1.2-PROPANEDIOL IS PROGRESSIVELY REPLACED BY METHANOL IN AQUEOUS SOLUTIONS WITH 35% SOLUTES, THE GLASS-FORMING TENDENCY REMAINS CONSTANT UP TO 20% METHANOL (1.2-PROPANEDIOL + METHANOL) THEN DECREASES. THIS APPEARS TO BE RELATED TO THE DIFFICULTY OF CRYSTALLIZATION OF THE METHANOL HYDRATE. THEREFORE UP TO 20% 1.2-PROPANEDIOL MAY BE REPLACED BY METHANOL WITHOUT DIMINISHING THE ABILITY TO OBTAIN COMPLETE VITRIFICATION OF CELL SOLUTIONS IF CELLS BETTERWITHSTAND SUCH SOLUTIONS THAN THOSE WHERE 1.2-PROPANEDIOL IS THE SINGLE CRYOPROTECTANT.

Details

  • Original title: STABILITY OF THE AMORPHOUS STATE IN THE SYSTEM WATER-1.2-PROPANEDIOL-METHANOL.
  • Record ID : 1986-1300
  • Languages: English
  • Source: Cryo-Letters - vol. 6 - n. 6
  • Publication date: 1985
  • Document available for consultation in the library of the IIR headquarters only.

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