IIR document

The effect of freeze-drying on the infectivity of herpes simplex virus (HSV)-2.

Author(s) : ZHAI S., SLATER N. H. K.

Summary

Freeze-drying is a widely used method for the stabilisation of delicate biopharmaceuticals. However a significant fraction of viability can be lost during processing due to stresses that occur in both the freezing and drying stages. Here the effect of the freezing rate on the recovery of herpes simplex virus 2 (HSV-2) infectivity in the presence of varying concentrations of cryoprotectant recipients was reported.

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Pages: 2004-1

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Details

  • Original title: The effect of freeze-drying on the infectivity of herpes simplex virus (HSV)-2.
  • Record ID : 2005-2281
  • Languages: English
  • Source: Cryogenics 2004. Proceedings of the 8th Cryogenics Conference
  • Publication date: 2004/04/27

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