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The role of cell-cell contact on intracellular ice formation.

Author(s) : ACKER J. P., MCGANN L. E.

Type of article: Article

Summary

Cell-cell and cell-surface interactions have been shown to enhance the susceptibility of cells to intracellular ice formation. A study using hamster fibroblast cells was conducted to correlate the effects of cell-cell contact on the incidence and distribution of intracellular ice formation in cell monolayers. Cryomicroscopy and video image analysis were used to examine the relationship between intracellular ice formation in cells in relative proximity to one another. The probability and kinetics of intracellular ice formation in a cell increased when an adjacent cell froze intracellularly. Statistical analysis supports the hypothesis that cell-cell contact increases the incidence of intracellular ice formation.

Details

  • Original title: The role of cell-cell contact on intracellular ice formation.
  • Record ID : 1999-3910
  • Languages: English
  • Source: Cryo-Letters - vol. 19 - n. 6
  • Publication date: 1998/11
  • Document available for consultation in the library of the IIR headquarters only.

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