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AN IRREVERSIBLE THERMODYNAMIC ANALYSIS OF CELL FREEZING IN THE PRESENCE OF MEMBRANE-PERMEABLE ADDITIVES. III. TRANSIENT WATER AND ADDITIVES FLUXES.

Author(s) : DILLER K. R., LYNCH M. E.

Type of article: Article

Summary

THE SIMULTANEOUS, COUPLED TRANSPORT OF WATER AND GLYCEROL ACROSS THE CELL MEMBRANE DURING FREEZING IS MODELLED BY THE METHODS OF IRREVERSIBLE THERMODYNAMICS. PROTOCOLS ARE SIMULATED FOR COOLING RATES BETWEEN 55 AND 5,000 K/MIN AND GLYCEROL CONCENTRATIONS BETWEEN 0.4 AND 3.0 MOLAR. VALUES WERE CALCULATED FOR THE INSTANTANEOUS WATER AND ADDITIVE FLUXES AND THE TRANSIENT VOLUME OF GLYCEROL INTERIOR TO THE CELL. THE RESULTS INDICATE A STRONG DEPENDENCY OF THE MAGNITUDE AND VARIATION OF THESE PARAMETERS ON BOTH THE COOLING RATE AND INITIAL ADDITIVE CONCENTRATION.

Details

  • Original title: AN IRREVERSIBLE THERMODYNAMIC ANALYSIS OF CELL FREEZING IN THE PRESENCE OF MEMBRANE-PERMEABLE ADDITIVES. III. TRANSIENT WATER AND ADDITIVES FLUXES.
  • Record ID : 1984-2472
  • Languages: English
  • Source: Cryo-Letters - vol. 5 - n. 2
  • Publication date: 1984
  • Document available for consultation in the library of the IIR headquarters only.

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