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Corneal tolerance of vitrifiable concentrations of glycerol.

Author(s) : RICH S. J., ARMITAGE W. J.

Type of article: Article

Summary

The study examined the effects on the structure and function of rabbit corneal endothelium of the low toxicity cryoprotectant glycerol. Endothelial structure was observed using specular microscopy during perfusion and scanning electron microscopy after perfusion. In all cases corneas initially showed signs of damage but endothelial function was regained following structural repair. Corneas exposed to 6.8 M glycerol and cooled below transition temperature were nonfunctional after warming. Ice formation during warming was believed to be the cause of injury.

Details

  • Original title: Corneal tolerance of vitrifiable concentrations of glycerol.
  • Record ID : 1993-0526
  • Languages: English
  • Source: Cryobiology - vol. 29 - n. 2
  • Publication date: 1992/04

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