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Effect of cryopreservation on the immunogenicity of pancreatic islets in xenotransplantation from pig to dog.

[In Japanese. / En japonais.]

Author(s) : IWASA K., IZUMI R., MIYAZAKI I.

Type of article: Article

Summary

The results indicated that isolating islets from cryopreserved pancreas tissue is as good as cryopreserving islets from fresh pancreas in yielding viable islets for transplantation. The survival of transplanted islets obtained by these two methods was almost the same, whereas islets without cryopreservation were rejected almost immediately after xenotransplantation. The immunogenicity of pancreatic islets is reduced and graft survival is prolonged by cryopreservation, but it is impossible to avoid hyperacute rejection using the cryopreservation technique performed in the study.

Details

  • Original title: [In Japanese. / En japonais.]
  • Record ID : 1996-3747
  • Languages: Japanese
  • Source: Low Temperature Medicine - vol. 22 - n. 1
  • Publication date: 1996/01
  • Document available for consultation in the library of the IIR headquarters only.

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