PROTECTIVE EFFECT OF CRYOPROTECTANTS ON HUMAN PLATELETS AFTER REPEATED FREEZE-THAW CYCLES.

Author(s) : RACZ Z.

Type of article: Article

Summary

FREEZE-THAW CYCLES WERE REPEATED THREE TIMES SUCCESSIVELY. CELLULAR DAMAGE WAS INDICATED BY THE ACTIVITY OF THE ACID PHOSPHATASE ENZYME RELEASED FROM THE PLATELETS. AFTER THE FIRST FREEZE-THAW CYCLE SUBSTANCES POSSESSING EFFECTIVE H-BONDING PROPERTIES (GLYCEROL AND PEG 400) SHOWED A SIMILAR EFFECT TO DMSO. THERE WAS A CHANGE FOLLOWING THE 2ND CYCLE AND AFTER THE THIRD CYCLE DMSO BECAME THE MOST EFFECTIVE CRYOPROTECTANT.

Details

  • Original title: PROTECTIVE EFFECT OF CRYOPROTECTANTS ON HUMAN PLATELETS AFTER REPEATED FREEZE-THAW CYCLES.
  • Record ID : 1984-2118
  • Languages: English
  • Source: Cryo-Letters - vol. 4 - n. 3
  • Publication date: 1983
  • Document available for consultation in the library of the IIR headquarters only.

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