PROTECTIVE EFFECT OF CRYOPROTECTANTS ON HUMAN PLATELETS AFTER REPEATED FREEZE-THAW CYCLES.
Author(s) : RACZ Z.
Type of article: Article
Summary
FREEZE-THAW CYCLES WERE REPEATED THREE TIMES SUCCESSIVELY. CELLULAR DAMAGE WAS INDICATED BY THE ACTIVITY OF THE ACID PHOSPHATASE ENZYME RELEASED FROM THE PLATELETS. AFTER THE FIRST FREEZE-THAW CYCLE SUBSTANCES POSSESSING EFFECTIVE H-BONDING PROPERTIES (GLYCEROL AND PEG 400) SHOWED A SIMILAR EFFECT TO DMSO. THERE WAS A CHANGE FOLLOWING THE 2ND CYCLE AND AFTER THE THIRD CYCLE DMSO BECAME THE MOST EFFECTIVE CRYOPROTECTANT.
Details
- Original title: PROTECTIVE EFFECT OF CRYOPROTECTANTS ON HUMAN PLATELETS AFTER REPEATED FREEZE-THAW CYCLES.
- Record ID : 1984-2118
- Languages: English
- Source: Cryo-Letters - vol. 4 - n. 3
- Publication date: 1983
- Document available for consultation in the library of the IIR headquarters only.
Links
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Indexing
- Themes: The influence of refrigeration on cells, tissues and organs
- Keywords: Thawing; Platelet; Cryoprotectant; DMSO; Blood; Glycerol; Enzyme; Cryopreservation
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- Author(s) : RACZ Z.
- Date : 1984
- Languages : English
- Source: Cryo-Letters - vol. 5 - n. 2
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- Author(s) : ARMITAGE W. J.
- Date : 1982
- Languages : English
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- Author(s) : ARNAUD F.
- Date : 1987
- Languages : English
- Source: Cryo-Letters - vol. 8 - n. 5
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- Author(s) : BAYTHOON H., TUDDENHAM E. G. D., HUTTON R. A.
- Date : 1982
- Languages : English
- Source: J. clin. Pathol. - vol. 35 - n. 8
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- Author(s) : SPECTOR J. I., FLOR W. J., VALERI C. R.
- Date : 1979
- Languages : English
- Source: Transfusion - vol. 19 - n. 3
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