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Studying the mechanism of deep cooling of warm-blooded animals.

Author(s) : ROMANETS K. M., SKORNYAKOV B. A., KOPTELOV V. A., FEREIRA A., GIRICH S. O.

Summary

Deep cooling of rats down to 21 deg C results in their death when trying to warm them due to impairments in functioning of many systems of the organism. In the in vivo experiments, the authors observed considerable alterations in the hormonal pattern, and an increase in the total esterase activity of rat blood plasma. At the same time premedication with cryoprotectants greatly improves the animal survival rate. Experiments are described and results are given. A possibility exists of applying classic cryoprotectants as protective agents during hypothermia.

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Pages: 75-81

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Details

  • Original title: Studying the mechanism of deep cooling of warm-blooded animals.
  • Record ID : 1996-1207
  • Languages: English
  • Source: For a Better Quality of Life. 19th International Congress of Refrigeration.
  • Publication date: 1995/08/20
  • Document available for consultation in the library of the IIR headquarters only.

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