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Vaccinating children beyond the cold chain: towards less heat-sensitive vaccines.

Vacciner les enfants au-delà de la "chaine de froid" : pour des vaccins moins sensibles à la chaleur.

Type of monograph: Report

Summary

Vaccines have to be kept under recommended storage conditions that guarantee the maintenance of their quality during production, storage, handling, transportation and use. As a result, extensive measures are put in place to avoid exposure of the product to inappropriate temperatures. Almost all vaccines used in immunization programs today are licensed for storage and distribution within a temperature-controlled supply chain of between 2°C and 8°C. However, keeping vaccines within this range is extremely difficult in countries with limited cold chain and ice pack production capacity. Immunization programs therefore would benefit greatly from novel approaches to vaccine stability assessment and management that would permit the use of product at ambient temperatures, in a controlled temperature chain (CTC) for defined periods of time, as appropriate to the stability profile of the antigen.

Details

  • Original title: Vacciner les enfants au-delà de la "chaine de froid" : pour des vaccins moins sensibles à la chaleur.
  • Record ID : 30012537
  • Languages: French
  • Subject: Developing country
  • Publication: Médecins sans frontières - Switzerland/Switzerland
  • Publication date: 2014/04

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