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CONTRIBUTIONS OF UNFROZEN FRACTION AND OF SALT CONCENTRATION TO THE SURVIVAL OF SLOWLY FROZEN HUMAN ERYTHROCYTES: INFLUENCE OF WARMING RATE.

Author(s) : MAZUR P., RIGOPOULOS N.

Type of article: Article

Summary

THE GENERAL BELIEF IS THAT SLOW FREEZING INJURY IS EITHER THE RESULT OF EXPOSURE TO HIGH SALT CONCENTRATIONS OR THE RESULT OF EXCESSIVE CELL SHRINKAGE. WHEN HUMAN RED CELLS ARE FROZEN UNDER THESE CONDITIONS AND THAWED RAPIDLY, SURVIVAL IS MORE DEPENDENT ON THE UNFROZEN WATER FRACTION THAN IT IS ON THE SALT CONCENTRATION IN THAT FRACTION. THE PRESENT WORK COMPARES THESE RESULTS WITH THOSE OBTAINED WITH SLOW THAWING.

Details

  • Original title: CONTRIBUTIONS OF UNFROZEN FRACTION AND OF SALT CONCENTRATION TO THE SURVIVAL OF SLOWLY FROZEN HUMAN ERYTHROCYTES: INFLUENCE OF WARMING RATE.
  • Record ID : 1984-1243
  • Languages: English
  • Source: Cryobiology - vol. 20 - n. 3
  • Publication date: 1983

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