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Current status of cryopreservation of pancreatic islets.

[In Japanese. / En japonais.]

Author(s) : KIMURA T., KOJIMA Y., NAKAGAWARA G.

Type of article: Article, Review

Summary

With rodents, islets were cryopreserved without a loss of biological abilities. But clinical studies have some problems. In 1990-1992, the combined transplantation of freshly isolated and/or cultured islets with cryopreserved/thawed islet tissue was reported in 10 cases, and cryopreserved/thawed islet tissue alone was only transplanted in 5 cases. For these two groups, the number of patients who showed basal C-peptide more or equal 1 ng/ml at more or equal 1 month was 8 (80%), and 2 (40%), and the number of insulin independent patient was 4 (40%) and 0 (0%). A better outcome might be achievable.

Details

  • Original title: [In Japanese. / En japonais.]
  • Record ID : 1996-3745
  • Languages: Japanese
  • Source: Low Temperature Medicine - vol. 22 - n. 1
  • Publication date: 1996/01
  • Document available for consultation in the library of the IIR headquarters only.

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