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ERYTHROCYTES IN 1,2-BUTANEDIOL: < TOXICITY > AND CRYOPROTECTION.

Author(s) : MEHL P., BOUTRON P.

Type of article: Article

Summary

WITH 20% 1,2-BUTANEDIOL, SURVIVAL RATES OR ERYTHROCYTES COOLED DOWN TO 77 K (-196 DEG C) SHOW A CLASSICAL MAXIMUM OF 80% OF SURVIVAL FOR COOLING RATES OF ABOUT 1 TO 1.8 K/S WHEN SUBSEQUENT WARMING IS RAPID. THE TOXICITY OF THIS COMPOUND DOES NOT ALLOW STUDIES OF CRYOPROTECTION FOR HIGHER CONCENTRATIONS. ERYTHROCYTES HEMOLYSE RAPIDLY AT 273 K (0 DEG C) IN BUFFERED SOLUTIONS WITH 25% OR MORE 1,2-BUTANEDIOL.

Details

  • Original title: ERYTHROCYTES IN 1,2-BUTANEDIOL: < TOXICITY > AND CRYOPROTECTION.
  • Record ID : 1987-2024
  • Languages: English
  • Source: Cryo-Letters - vol. 7 - n. 6
  • Publication date: 1986
  • Document available for consultation in the library of the IIR headquarters only.

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