LONG-TERM NORMOGLYCEMIA IN PANCREATECTOMIZED DOGS TRANSPLANTED WITH FROZEN-THAWED PANCREATIC ISLETS.
Author(s) : KNETEMAN N. M., RAJOTTE R. V., WARNOCK G. L.
Type of article: Article
Summary
THE AUTHORS REPORT SUCCESS ON LONG-TERM FOLLOW-UP WITH AUTOTRANSPLANTATION OF FROZEN-THAWED CANINE PANCREATIC FRAGMENTS. CRYOPRESERVATION WAS BY DMSO EQUILIBRATION, COOLING AT 0.25 K/MIN TO 198 K (-75 DEG C), STORAGE IN LIQUID N2 AND THAWING AT 3.5 K/MIN. FOUR OF FIVE ACUTELY AUTOTRANSPLANTED DOGS REMAINED NORMOGLYCEMIC FOR 20 MONTHS. CRYOPRESERVATION PRESERVED VIABILITY OF SUFFICIENT CANINE PANCREATIC ISLETS TO REVERSE DIABETES WITH AUTOTRANSPLANTATION.
Details
- Original title: LONG-TERM NORMOGLYCEMIA IN PANCREATECTOMIZED DOGS TRANSPLANTED WITH FROZEN-THAWED PANCREATIC ISLETS.
- Record ID : 1987-0764
- Languages: English
- Source: Cryobiology - vol. 23 - n. 3
- Publication date: 1986
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- Date : 1987
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