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Supplemented phase diagram of the trehalose-water binary mixture. Literature review.

Author(s) : CHEN T., FOWLER A, TONER M.

Type of article: Article

Summary

Trehalose is very useful in many fields, including freeze-drying, cryoprotection, and anhydrobiosis. In this study, literature data for the binary trehalose-water system were collected and analysed. The literature data were found to be reasonably consistent, with substantial agreement on the melting points for water, trehalose, and trehalose dehydrate and the glass transition temperature of water. There was also good agreement for the solubility, freezing, and glass transition curves. However, there was no general agreement on the glass transition temperature of pure trehalose. The trehalose-water glass transition curve was modelled using the Gordon-Taylor equation, with a value for k of 5.2. The collected data in this report will be of much use in further studies of the protective abilities of trehalose.

Details

  • Original title: Supplemented phase diagram of the trehalose-water binary mixture. Literature review.
  • Record ID : 2001-1385
  • Languages: English
  • Source: Cryobiology - vol. 40 - n. 3
  • Publication date: 2000/05

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