ShareCHANGES IN THE PERMEABILITY CHARACTERISTICS OF ISOLATED HEPATOCYTES DURING SLOW FREEZING.
Author(s) : FULLER B. J., LOECKER W. de
Type of article: Article
Summary
ISOLATED HEPATOCYTES HAVE BEEN USED TO STUDY CHANGES IN MEMBRANE PERMEABILITY DURING A FREEZE/THAW CYCLE. ON COOLING FROM 310 K (37 DEG C) TO VARIOUS INTERMEDIATE TEMPERATURES DOWN TO 253 K (-20 DEG C) THEREWAS A TREND FOR INCREASE IN CELL SODIUM AND WATER CONTENT, REACHING SIGNIFICANCE AT 263 K (-10 DEG C). MEMBRANE PERMEABILITY TO SUCROSE ALSO INCREASED BY A SMALL BUT SIGNIFICANT AMOUNT ON COOLING BELOW 263 K.
Details
- Original title: CHANGES IN THE PERMEABILITY CHARACTERISTICS OF ISOLATED HEPATOCYTES DURING SLOW FREEZING.
- Record ID : 1986-1302
- Languages: English
- Source: Cryo-Letters - vol. 6 - n. 6
- Publication date: 1985
- Document available for consultation in the library of the IIR headquarters only.
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Indexing
- Themes: The influence of refrigeration on cells, tissues and organs
- Keywords: Cell; Survival; Permeability; Membrane; Freezing-thawing; Freezing; Liver
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