COMPARATIVE EFFECT OF CRYOPROTECTANTS ON RABBIT EMBRYOS CYTOSKELETON.

Author(s) : VINCENT C.

Type of article: Article

Summary

THE COMPARATIVE EFFECTOF 1-2-PROPANEDIOL AND DMSO ON ONE CELL RABBIT EMBRYO SURVIVAL AFTER FREEZING AND THAWING WAS STUDIED. THE ACTION OF THESE SOLVENTS ON ACTIN DEPOLYMERIZATION WAS EXAMINED BOTH IN EMBRYOS AND IN VITRO. THE HIGH SURVIVAL RATE OBTAINED WITH PROPANEDIOL (72%) AS COMPARED TO DMSO (44%) CAN BE PARTLY ASCRIBED TO ITS DEPOLYMERIZING EFFECT ON MICROFILAMENTS. THE RESULTS SUGGEST THAT MAINTAINING THE ACTIN-LINKED CYTOSKELETON INTEGRITY MAY NOT BE BENEFICIAL TO CRYOPRESERVATION.

Details

  • Original title: COMPARATIVE EFFECT OF CRYOPROTECTANTS ON RABBIT EMBRYOS CYTOSKELETON.
  • Record ID : 1989-0374
  • Languages: English
  • Source: Cryo-Letters - vol. 8 - n. 6
  • Publication date: 1987
  • Document available for consultation in the library of the IIR headquarters only.

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