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Temperature threshold and preservation of signaling for mitochondrial membrane proteins during ischemia in rabbit heart.

Author(s) : NING X. H., XU C. S., SONG Y. C., XIAO Y., HU Y. J., LUPINETTI F. M., PORTMAN M. A.

Type of article: Article

Summary

Myocardial protection induced by hypothermic adaptation preserves expression of genes regulating heat shock protein and the nuclear-encoded mitochondrial proteins. This preservation is associated with a reduction in ATP depletion similar to that noted in cardioplegic arrested hearts preserved at a critical temperature (30 deg C) or below. The authors tested the hypothesis that expression of these genes may also be subject to this temperature threshold phenomenon.

Details

  • Original title: Temperature threshold and preservation of signaling for mitochondrial membrane proteins during ischemia in rabbit heart.
  • Record ID : 1999-3254
  • Languages: English
  • Source: Cryobiology - vol. 36 - n. 4
  • Publication date: 1998/06

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