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SIMPLIFIED CALCULATION OF CELL WATER CONTENT DURING FREEZING AND THAWING IN NONIDEAL SOLUTIONS OF CRYOPROTECTIVE AGENTS AND ITS POSSIBLE APPLICATION TO THE STUDY OF INJURY.

Author(s) : FAHY G. M.

Type of article: Article

Summary

A SIMPLIFIED EQUATION HAS BEEN DERIVED WHICH REDUCES THE TIME AND COMPLEXITY OF CALCULATING SUBZERO CELL WATER CONTENT DURING FREEZING AND THAWING AS COMPARED TO CALCULATION BY MEANS OF THE MAZUR EQUATION, AND IT ALSO ALLOWS INCLUSION OF THE EFFECTS OF NONIDEALITY OF GLYCEROL AND DIMETHYL SULFOXIDE AQUEOUS ELECTROLYTE SOLUTIONS. IT IS HOPED THAT THESE SIMPLIFICATIONS WILL MAKE CALCULATION OF CELL WATER CONTENT ACCESSIBLE TO MORE CRYOBIOLOGISTS. IN ADDITION, POSSIBLE APPLICATIONS OF SUCH CALCULATIONS TO MECHANISTIC ISSUES IN THE AREA OF INJURY ARE DISCUSSED.

Details

  • Original title: SIMPLIFIED CALCULATION OF CELL WATER CONTENT DURING FREEZING AND THAWING IN NONIDEAL SOLUTIONS OF CRYOPROTECTIVE AGENTS AND ITS POSSIBLE APPLICATION TO THE STUDY OF INJURY.
  • Record ID : 1982-1743
  • Languages: English
  • Source: Cryobiology - vol. 18 - n. 5
  • Publication date: 1981

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