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THE RELEVANCE OF CRYOPROTECTANT < TOXICITY > TO CRYOBIOLOGY.

Author(s) : FAHY G. M.

Type of article: Article

Summary

CRYOPROTECTIVE AGENTS DO NOT USUALLY PERMIT 100% SURVIVAL AFTER FREEZING AND THAWING, THOUGH FROM A THEORETICAL POINT OF VIEW THEY SHOULD BE ABLE TO FULLY SUPPRESS ALL KNOWN TYPES OF FREEZING INJURY. IT IS SUGGESTED THAT THE TOXICITY OF THESE AGENTS IS A KEY LIMITING FACTORIN CRYOBIOLOGY. NOT ONLY DOES THIS TOXICITY PREVENT THE USE OF FULLY PROTECTIVE LEVELS OF ADDITIVE, BUT IT MAY ALSO BE MANIFESTED IN THE FORM OF CRYOINJURY. EVIDENCE FOR THE CRYOPROTECTANT-ASSOCIATED FREEZING INJURY IS REVIEWED. IT IS SUGGESTED THAT BETTER SUPPRESSION OF TOXICITY IS POSSIBLE.

Details

  • Original title: THE RELEVANCE OF CRYOPROTECTANT < TOXICITY > TO CRYOBIOLOGY.
  • Record ID : 1986-2530
  • Languages: English
  • Source: Cryobiology - vol. 23 - n. 1
  • Publication date: 1986

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