Summary
Freeze-drying is an important preservation technique for heat-sensitive pharmaceuticals and foods. Products are first frozen, then dried in a vacuum at low temperature by sublimation and desorption, rather than by the application of heat. The resulting items can be stored at room temperature for long periods. This informative text addresses both principles and practice in this area. The first chapter introduces freeze-drying. The authors then review the fundamentals of the technique, heat-mass transfer analyses, modelling of the drying process and the equipment employed. Further chapters focus on freeze-drying of food, freeze-drying of pharmaceuticals and the protective agents and additives applied. The final chapter covers the important subjects of disinfection, sterilization and process validation.
Details
- Original title: Freeze-drying/lyophilization of pharmaceutical and food products.
- Record ID : 2010-1696
- Languages: English
- Subject: Technology
- Publication: Woodhead - United kingdom/United kingdom
- Publication date: 2010
- Collection:
- ISBN: 9781845697464
- Source: Source: WPF 198; 273 p.; fig.; tabl.; ref.; index.
- Notes:
Published in North America by CRC Press (USD 195). Published in China by Science Press.
- Document available for consultation in the library of the IIR headquarters only.
Links
- External links:
Indexing
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Themes:
Freeze-drying in biology and medicine;
Freeze-drying of foodstuffs and other products - Keywords: Thermal property; Technology; Sterilization; Refrigerating system; Freeze-drying; Freeze-dried product; Food; Calculation; Measurement; Mass transfer; Heat transfer; Storage; Modelling; Pharmaceutical industry; HACCP; Case study; Equipment; Disinfection; Freezing; Additive
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