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Freeze-drying. Rarified atmosphere in a freeze-drier: impact on the preservation of freeze-dried products.

La lyophilisation. L'atmosphère raréfiée dans un lyophilisateur : influence sur la conservation des lyophilisats.

Author(s) : AMOIGNON J.

Type of monograph: Book

Summary

Applications for freeze-drying are numerous; particularly in the biological, pharmaceutical, cosmetics and food sectors. Less known is its use in museology and in the processing of graphics documents of which the medium (paper, parchment, leather) has accidentally been immersed in a liquid. Even more unexpected is the freeze-drying of objects obtained from digs in moist or aquatic environments that are sometimes thousands of years old (e.g. the neolithic era). Some still little-known phenomena are neglected due to their random nature, although they can lead to a loss in the product or a serious deterioration in its quality. Freezing is the first phase in a freeze-drying process. Crystallization is dependent on the way in which it is carried out, i.e. the end quality of the product and the time needed to obtain it. The freeze-dried product is a remarkable adsorbent in an enclosed space. Extraneous flows (gas purging, permeation, air-tightness) occur and if these flows are significant, they can alter the product following packaging (contamination). Freeze-drying cycles are generally well controlled but this is dependent on the performance limits of the equipment. An entire chapter is devoted to freeze-drying at atmospheric pressure.

Details

  • Original title: La lyophilisation. L'atmosphère raréfiée dans un lyophilisateur : influence sur la conservation des lyophilisats.
  • Record ID : 2006-0502
  • Languages: French
  • Publication: LeeM Services - France/France
  • Publication date: 2005
  • ISBN: 2951578458
  • Source: Source: ed. 3; 108 p. (20.7 x 29.3); fig.; tabl.; 14 ref.; EUR 27.60.
  • Document available for consultation in the library of the IIR headquarters only.

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