SKIN PRESERVATION AT 277 K (4 DEG C): A SPECIES COMPARISON.

Author(s) : ROSENQUIST M. D., CRAM A. E., KEALEY G. P.

Type of article: Article

Summary

DONOR SKIN WAS OBTAINED FROM 5 ANIMAL SPECIES AND HUMAN SURGICAL PANNICULECTOMY SPECIMENS. SKIN STORED AT 277 K WAS TRANSPLANTED TO SURGICALLY CREATED DEFECTS ON MICE AFTER SPECIFIC STORAGE INTERVALS. THE VIABILITY OF MOUSE, RAT, AND DOG SKIN WAS SIGNIFICANTLY DIFFERENT FROM HUMAN SKIN, WHILE RABBIT AND PIG SKIN WERE SIMILAR TO HUMAN SKIN. THESE RESULTS DEMON-STRATE THE DIFFICULTY OF APPLYING THE DATA OF SKIN STORAGE STUDIES FROM NONHUMAN SPECIES TO CLINICAL PRACTICE. RABBIT AND PIG SKIN MAY BE USED IN LABORATORY STUDIES OF SKIN PRESERVATION AT 277 K WITH A LIKELIHOOD THAT THE RESULTS MAY BE OF CLINICAL RELEVANCE IN PREDICTING THE BEHAVIOUR OF HUMAN SKIN.

Details

  • Original title: SKIN PRESERVATION AT 277 K (4 DEG C): A SPECIES COMPARISON.
  • Record ID : 1989-0365
  • Languages: English
  • Source: Cryobiology - vol. 25 - n. 1
  • Publication date: 1988

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